Structure-Based Design of Glycosylated Oxytocin Analogues with Improved Selectivity and Antinociceptive Activity-Reference-Cited by-同舟云学术

Structure-Based Design of Glycosylated Oxytocin Analogues with Improved Selectivity and Antinociceptive Activity

Published:2023-01-24 Issue:2 Volume:14 Page:163-170
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Szabó Lajos Z.¹,Tanguturi Parthasaradhireddy²,Goodman Hannah J.¹^ORCID,Sprőber Sára¹³,Liu Chenxi¹^ORCID,Al-Obeidi Fahad¹,Bartlett Mitchell J.⁴,Falk Torsten²⁴,Kumirov Vlad K.¹,Heien M. Leandro¹⁵^ORCID,Streicher John M.¹⁵,Polt Robin¹^ORCID

Affiliation:

1. Department of Chemistry and Biochemistry, The University of Arizona, Tucson, Arizona85721, United States

2. Department of Pharmacology, College of Medicine, The University of Arizona, Tucson, Arizona85724, United States

3. Visiting Student, Budapest University of Technology and Economics, 1111Budapest, Műegyetem rkp. 3, Hungary

4. Department of Neurology, College of Medicine, The University of Arizona, Tucson, Arizona85724, United States

5. Comprehensive Pain and Addiction Center, The University of Arizona, Tucson, Arizona85724, United States

Funder

University of Arizona

Ethel and James Flinn Foundation

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.2c00455

Reference63 articles.

1. Oxycodone in the Opioid Epidemic: High ‘Liking’, ‘Wanting’, and Abuse Liability

2. Structural Insights Accelerate the Discovery of Opioid Alternatives

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5. Potential unintended consequences of class-wide drug scheduling based on chemical structure: A cautionary tale for fentanyl-related compounds

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