Multicomponent Macrocyclic IL-17a Modifier-Reference-Cited by-同舟云学术

Multicomponent Macrocyclic IL-17a Modifier

Published:2022-08-12 Issue:9 Volume:13 Page:1468-1471
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Abdelraheem Eman¹²,Lubberink Max¹,Wang Wenja¹,Li Jingyao¹,Reyes Romero Atilio¹,van der Straat Robin¹,Du Xiaochen¹,Groves Matthew¹^ORCID,Dömling Alexander¹^ORCID

Affiliation:

1. Department of Pharmacy, Drug Design Group, University of Groningen, A. Deusinglaan 1, Groningen 9700 AV, The Netherlands

2. Chemistry Department, Faculty of Science, Sohag University, Sohag 82524, Egypt

Funder

China Scholarship Council

Innovatieve Actieprogramma Groningen

Sanofi Type 2 Innovation

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.2c00257

Reference25 articles.

1. Critical role of interleukin (IL)-17 in inflammatory and immune disorders: An updated review of the evidence focusing in controversies

2. Interleukin-17 in Chronic Inflammatory Neurological Diseases

3. A Binding Site on IL-17A for Inhibitory Macrocycles Revealed by Hydrogen/Deuterium Exchange Mass Spectrometry

4. Inhibiting complex IL-17A and IL-17RA interactions with a linear peptide

5. Binding site elucidation and structure guided design of macrocyclic IL-17A antagonists

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