Fragment-Based Screen of SARS-CoV-2 Papain-like Protease (PL<sup>pro</sup>)-Reference-Cited by-同舟云学术

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Fragment-Based Screen of SARS-CoV-2 Papain-like Protease (PL^pro)

Published:2024-07-23 Issue:8 Volume:15 Page:1351-1357
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Taylor Ashley J.¹^ORCID,Amporndanai Kangsa¹^ORCID,Rietz Tyson A.¹^ORCID,Zhao Bin¹,Thiruvaipati Anusha¹^ORCID,Wei Qiangqiang¹,South Taylor M.¹,Crow Mackenzie M.¹,Apakama Chideraa¹,Sensintaffar John L.¹,Phan Jason¹,Lee Taekyu¹,Fesik Stephen W.¹²³^ORCID

Affiliation:

1. Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee 37232-0146, United States

2. Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232-6600, United States

3. Department of Chemistry, Vanderbilt University, Nashville, Tennessee 37235, United States

Funder

Vanderbilt University

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.4c00238

Reference29 articles.

1. Remdesivir: A Review of Its Discovery and Development Leading to Emergency Use Authorization for Treatment of COVID-19

2. Discovery, Development, and Patent Trends on Molnupiravir: A Prospective Oral Treatment for COVID-19

3. An oral SARS-CoV-2 M pro inhibitor clinical candidate for the treatment of COVID-19

4. Molecular mechanisms of SARS-CoV-2 resistance to nirmatrelvir

5. Naturally Occurring Mutations of SARS-CoV-2 Main Protease Confer Drug Resistance to Nirmatrelvir

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