Discovery of Novel Seven-Membered Prostacyclin Analogues as Potent and Selective Prostaglandin FP and EP3 Dual Agonists-Reference-Cited by-同舟云学术

Discovery of Novel Seven-Membered Prostacyclin Analogues as Potent and Selective Prostaglandin FP and EP3 Dual Agonists

Published:2016-12-16 Issue:1 Volume:8 Page:107-112
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Sugimoto Isamu¹²^ORCID,Kambe Tohru¹²,Okino Tomotaka¹²,Obitsu Tetsuo¹²,Ohta Nobukazu¹²,Nishiyama Taihei¹²,Kinoshita Akihiro¹²,Fujimoto Taku¹²,Egashira Hiromu¹²,Yamane Shinsaku¹²,Shuto Satoshi¹²^ORCID,Tani Kousuke¹²,Maruyama Toru¹²

Affiliation:

1. Medicinal Chemistry Research Laboratories, ‡Department of Biology & Pharmacology, and §Discovery Research Alliance, Ono Pharmaceutical Co., Ltd., 3-1-1 Sakurai, Shimamoto-cho, Mishima-gun, Osaka 618-8585, Japan

2. Faculty of Pharmaceutical Sciences and #Center for Research and Education on Drug Discovery, Hokkaido University, Kita-12, Nishi-6, Kita-Ku, Sapporo 060-0812, Japan

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.6b00415

Reference19 articles.

1. Phenyl-substituted prostaglandins: potent and selective antiglaucoma agents

2. Travoprost compared with latanoprost and timolol in patients with open-angle glaucoma or ocular hypertension

3. New Fluoroprostaglandin F2.ALPHA. Derivatives with Prostanoid FP-Receptor Agonistic Activity as Potent Ocular-Hypotensive Agents

4. Synthesis of the highly potent prostanoid FP receptor agonist, AFP-168: a novel 15-deoxy-15,15-difluoroprostaglandin F 2α derivative

5. The Effects of Prostaglandin Analogues on Prostanoid EP1, EP2, and EP3 Receptor-Deficient Mice

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1. Recent Developments for the Treatment of Glaucoma;Topics in Medicinal Chemistry;2020

2. Seven-Membered Rings;Progress in Heterocyclic Chemistry;2018

3. Lewis Acid Mediated Cyclizations: Diastereoselective Synthesis of Six- to Eight-Membered Substituted Cyclic Ethers;Synthesis;2017-07-25