Discovery of 2′-α-C-Methyl-2′-β-C-fluorouridine Phosphoramidate Prodrugs as Inhibitors of Hepatitis C Virus-Reference-Cited by-同舟云学术

Discovery of 2′-α-C-Methyl-2′-β-C-fluorouridine Phosphoramidate Prodrugs as Inhibitors of Hepatitis C Virus

Published:2016-10-24 Issue:12 Volume:7 Page:1197-1201
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Zeng Debin¹,Zhang Rui¹,Nie Quandeng¹,Cao Lin¹,Shang Luqing¹,Yin Zheng¹

Affiliation:

1. State Key Laboratory of Elemento-Organic Chemistry, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Haihe Education Park, 38 Tongyan Road, Tianjin 300353, PR China

Funder

State Administration of Foreign Experts Affairs

Ministry of Education of the People's Republic of China

Ministry of Science and Technology of the People's Republic of China

National Natural Science Foundation of China

Tianjin Municipality

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.6b00270

Reference19 articles.

1. Isolation of a cDNA cLone Derived from a Blood-Borne Non-A, Non-B Viral Hepatitis Genome

2. Candidate Targets for Hepatitis C Virus-Specific Antiviral Therapy

3. The global burden of hepatitis C

4. Nucleotide Prodrugs for HCV Therapy

5. Treating hepatitis C: current standard of care and emerging direct-acting antiviral agents

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