Investigation of Covalent Warheads in the Design of 2-Aminopyrimidine-based FGFR4 Inhibitors-Reference-Cited by-同舟云学术

Investigation of Covalent Warheads in the Design of 2-Aminopyrimidine-based FGFR4 Inhibitors

Published:2021-03-22 Issue:4 Volume:12 Page:647-652
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Deng Wuqing¹,Chen Xiaojuan²,Jiang Kaili¹,Song Xiaojuan³,Huang Minhao³,Tu Zheng-Chao³,Zhang Zhang¹,Lin Xiaojing⁴,Ortega Raquel⁴,Patterson Adam V.⁵⁴,Smaill Jeff B.⁵⁴,Ding Ke¹^ORCID,Chen Suming⁶,Chen Yongheng²^ORCID,Lu Xiaoyun¹^ORCID

Affiliation:

1. School of Pharmacy, Jinan University, #601 Huangpu Avenue West, Guangzhou 510632, China

2. Department of Oncology, NHC Key Laboratory of Cancer Proteomics and Laboratory of Structural Biology, National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan 410008, China

3. Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, #190 Kaiyuan Avenue, Guangzhou 510530, China

4. Auckland Cancer Society Research Centre, School of Medical Sciences, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand

5. Maurice Wilkins Centre for Molecular Biodiscovery, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand

6. Yancheng Dafeng People’s Hospital, #139 Xingfu East Road, Dafeng District,Yancheng 224100, China

Funder

Ministry of Science and Technology of the People's Republic of China

Health Research Council of New Zealand

Jinan University

National Natural Science Foundation of China

Cancer Society Auckland Northland

Publisher

American Chemical Society (ACS)