The Growing Importance of Chirality in 3D Chemical Space Exploration and Modern Drug Discovery Approaches for Hit-ID
Author:
Affiliation:
1. Department of Chemistry University of Liverpool, Liverpool ChiroChem, Ltd., Crown Street, Liverpool L69 7ZD, United Kingdom
Funder
Liverpool ChiroChem
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.1c00251
Reference87 articles.
1. The market of chiral drugs: Chiral switches versus de novo enantiomerically pure compounds
2. The predicated demise of racemic new molecular entities is an exaggeration
3. Atropisomerism in medicinal chemistry: challenges and opportunities
4. Molecular Shape Diversity of Combinatorial Libraries: A Prerequisite for Broad Bioactivity
Cited by 32 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Phosphosulindac (OXT-328) prevents and reverses chemotherapy induced peripheral neuropathy in mice;Frontiers in Neuroscience;2024-01-29
2. Conformational and Chiroptical Properties of Salicylamide-Based Peptidomimetics;Symmetry;2024-01-24
3. Recent Strategies in the Nucleophilic Dearomatization of Pyridines, Quinolines, and Isoquinolines;Chemical Reviews;2024-01-02
4. Double cobalt-catalyzed atroposelective C–H activation: One-step synthesis of atropisomeric indoles bearing vicinal C–C and C–N diaxes;Chem Catalysis;2023-10
5. Determination of the Handedness of Urea Inclusion Compounds;Chemistry – A European Journal;2023-09-25
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3