Conformational-Analysis-Guided Discovery of 2,3-Disubstituted Pyridine IDO1 Inhibitors-Reference-Cited by-同舟云学术

Conformational-Analysis-Guided Discovery of 2,3-Disubstituted Pyridine IDO1 Inhibitors

Published:2021-06-16 Issue:7 Volume:12 Page:1143-1150
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Cherney Emily C.¹^ORCID,Zhang Liping¹^ORCID,Guo Weiwei¹,Huang Audris¹,Williams David¹,Seitz Steven¹,Shan Weifang¹,Zhu Xiao¹^ORCID,Gullo-Brown Johnni¹,Maley Derrick¹,Lin Tai-an¹,Hunt John T.¹,Huang Christine¹,Yang Zheng¹,D’Arienzo Celia J.¹,Discenza Lorell N.¹,Ranasinghe Asoka¹,Grubb Mary F.¹,Traeger Sarah C.¹,Li Xin¹,Johnston Kathy A.¹,Kopcho Lisa¹,Fereshteh Mark¹,Foster Kimberly A.¹,Stefanski Kevin¹,Delpy Diane¹,Dhar Gopal²,Anandam Aravind²,Mahankali Sandeep²,Padmanabhan Shweta²,Rajanna Prabhakar²,Murali Venkata²,Mariappan T. Thanga²,Pattasseri Shabeerali²,Nimje Roshan Y.²,Hong Zhenqiu¹,Kempson James¹^ORCID,Rampulla Richard¹,Mathur Arvind¹,Gupta Anuradha²^ORCID,Borzilleri Robert¹,Vite Gregory¹,Balog Aaron¹

Affiliation:

1. Bristol Myers Squibb Research and Development, 3551 Lawrenceville, Princeton Road, Lawrence Township, New Jersey 08648, United States

2. Department of Discovery Synthesis, Biocon Bristol Myers Squibb R&D Centre, Syngene International Ltd., Biocon Park, Plot No. 2 & 3, Bommasandra−Jigani Road, Bangalore 560099, India

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.1c00236

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5. Blocking Indolamine-2,3-Dioxygenase Rebound Immune Suppression Boosts Antitumor Effects of Radio-Immunotherapy in Murine Models and Spontaneous Canine Malignancies

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