Antitarget Selectivity and Tolerability of Novel Pyrrolo[2,3-d]pyrimidine RET Inhibitors
Author:
Affiliation:
1. The Genomics Institute of the Novartis Research Foundation, 10675 John Jay Hopkins Drive, San Diego, California 92121, United States
2. Novartis Institutes for BioMedical Research, One Health Plaza, East Hanover, New Jersey 07936, United States
Funder
National Institute of General Medical Sciences
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.1c00450
Reference20 articles.
1. Activation of a novel human transforming gene, ret, by DNA rearrangement
2. The receptor tyrosine kinase RET regulates hindgut colonization by sacral neural crest cells
3. GDNF and the RET Receptor in Cancer: New Insights and Therapeutic Potential
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5. RET kinase inhibitors: a review of recent patents (2012–2015)
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1. Current scenario of fused pyrimidines with in vivo anticancer therapeutic potential;Archiv der Pharmazie;2024-05-16
2. Current Developments of Pyrrolo[2,3-d]pyrimidines with Anticancer Potential (A Review);Russian Journal of General Chemistry;2023-10
3. Recent Advances in the Development of RET Inhibitors;Letters in Drug Design & Discovery;2023-03-06
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