Discovery of Novel Indole Derivatives as Fructose-1,6-bisphosphatase Inhibitors and X-ray Cocrystal Structures Analysis-Reference-Cited by-同舟云学术

Discovery of Novel Indole Derivatives as Fructose-1,6-bisphosphatase Inhibitors and X-ray Cocrystal Structures Analysis

Published:2021-12-20 Issue:1 Volume:13 Page:118-127
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Wang Xiaoyu¹,Zhao Rui¹²,Ji Wenming³⁴,Zhou Jie¹,Liu Quan³⁴,Zhao Linxiang²^ORCID,Shen Zhufang³⁴,Liu Shuainan³⁴,Xu Bailing¹^ORCID

Affiliation:

1. Beijing Key Laboratory of Active Substances Discovery and Druggability Evaluation, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China

2. School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, Shenyang, 100016, China

3. State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China

4. Diabetes Research Center, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China

Funder

Natural Science Foundation of Beijing Municipality

Chinese Academy of Medical Sciences

National Natural Science Foundation of China

Beijing Outstanding Young Scientist Program

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.1c00613

Reference32 articles.

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4. Diabetic Retinopathy Guidelines; Scientific Department, The Royal College of Ophthalmologists, 2012; https://www.rcophth.ac.uk/wp-content/uploads/2014/12/2013-SCI-301-FINAL-DR-GUIDELINES-DEC-2012-updated-July-2013.pdf (accessed 2021-11-02).

5. Endothelial nitric oxide synthase (eNOS) 4b/a polymorphism and the risk of diabetic nephropathy in type 2 diabetes mellitus: A meta-analysis

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