Design and Evaluation of Bispidine-Based SARS-CoV-2 Main Protease Inhibitors

Author:

Shcherbakov Dmitriy12,Baev Dmitriy3,Kalinin Mikhail45,Dalinger Alexander5,Chirkova Varvara2,Belenkaya Svetlana16,Khvostov Aleksei5,Krut’ko Dmitry5,Medved’ko Aleksei4ORCID,Volosnikova Ekaterina1,Sharlaeva Elena2,Shanshin Daniil1,Tolstikova Tatyana3,Yarovaya Olga3ORCID,Maksyutov Rinat1,Salakhutdinov Nariman3,Vatsadze Sergey4ORCID

Affiliation:

1. State Research Center of Virology and Biotechnology VECTOR, Rospotrebnadzor, 630559, Russia, Koltsovo, Novosibirsk Region, Russian Federation

2. Altay State University, 656049, Barnaul, Leninski pr. 61, Russian Federation

3. N.N. Vorozhtsov Novosibirsk Institute of Organic chemistry SB RAS, Lavrent’ev av., 630090, Russia, Novosibirsk, Russian Federation

4. N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Leninski pr., 47, 119991 Moscow, Russian Federation

5. Department of Chemistry, M.V. Lomonosov Moscow State University, Leninskie Gory, 1-3, 119991 Moscow, Russian Federation

6. Novosibirsk State University, Novosibirsk Pirogova 1, 630090 Novosibirsk, Russian Federation

Funder

Russian Foundation for Basic Research

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

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