DL5050, a Selective Agonist for the Human Constitutive Androstane Receptor-Reference-Cited by-同舟云学术

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DL5050, a Selective Agonist for the Human Constitutive Androstane Receptor

Published:2019-06-12 Issue:7 Volume:10 Page:1039-1044
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Liang Dongdong¹,Li Linhao¹,Lynch Caitlin²,Diethelm-Varela Benjamin¹,Xia Menghang²,Xue Fengtian¹^ORCID,Wang Hongbing¹

Affiliation:

1. Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, Maryland 21201, United States

2. National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, Maryland 20892-3375, United States

Funder

National Center for Advancing Translational Sciences

National Institute of General Medical Sciences

Maryland Innovation Initiative

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.9b00079

Reference38 articles.

1. The nuclear receptor CAR mediates specific xenobiotic induction of drug metabolism

2. CAR and PXR: The xenobiotic-sensing receptors☆

3. An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids

4. Role reversal: new insights from new ligands for the xenobiotic receptor CAR

5. Identification of a Novel Human Constitutive Androstane Receptor (CAR) Agonist and Its Use in the Identification of CAR Target Genes

Cited by 10 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Evaluation of 2,3-dihydroimidazo[2,1-b]oxazole and imidazo[2,1–b]oxazole derivatives as chemotherapeutic agents;Future Medicinal Chemistry;2023-10

2. Discovery of Novel Human Constitutive Androstane Receptor Agonists with the Imidazo[1,2-a]pyridine Structure;Journal of Medicinal Chemistry;2023-02-09

3. Regulation of Nuclear Receptors PXR and CAR by Small Molecules and Signal Crosstalk: Roles in Drug Metabolism and Beyond;Drug Metabolism and Disposition;2022-09-18

4. Searching for Constitutive Androstane Receptor Modulators;Drug Metabolism and Disposition;2022-02-19

5. Synthesis and Evaluation of Antimicrobial and Anti-inflammatory Activity of 6-aryliden-2-methyl-2,3-dihydroimidazo[2,1-b][1,3]thiazoles;Biointerface Research in Applied Chemistry;2021-04-20

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