Structure–Activity Relationship Evaluation of Wasp Toxin β-PMTX Leads to Analogs with Superior Activity for Human Neuronal Sodium Channels
Author:
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.9b00415
Reference18 articles.
1. Toxins in Drug Discovery and Pharmacology
2. Knottins: disulfide-bonded therapeutic and diagnostic peptides
3. Structure and Modeling of Knottins, a Promising Molecular Scaffold for Drug Discovery
4. Selective Voltage-Gated Sodium Channel Peptide Toxins from Animal Venom: Pharmacological Probes and Analgesic Drug Development
5. Selective spider toxins reveal a role for the Nav1.1 channel in mechanical pain
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