Novel Sustainable-by-Design HDAC Inhibitors for the Treatment of Alzheimer’s Disease

Author:

Soares Romeiro Luiz Antonio12,da Costa Nunes Jéssica Larissa1,de Oliveira Miranda Camila1,Simões Heyn Roth Cardoso Gabriella1,de Oliveira Andressa Souza1,Gandini Annachiara34ORCID,Kobrlova Tereza5,Soukup Ondrej5,Rossi Michele3,Senger Johanna6,Jung Manfred6ORCID,Gervasoni Silvia7,Vistoli Giulio7ORCID,Petralla Sabrina3,Massenzio Francesca3,Monti Barbara3,Bolognesi Maria Laura3ORCID

Affiliation:

1. Department of Pharmacy, Health Sciences Faculty, University of Brasília, Campus Universitário Darcy Ribeiro, 70910-900 Brasília, DF, Brazil

2. LADETER, Catholic University of Brasilia, QS 07, Lote 01, EPCT, Águas Claras, 71966-700 Brasília, DF, Brazil

3. Department of Pharmacy and Biotechnology, Alma Mater Studiorum - University of Bologna, Via Belmeloro 6, I-40126 Bologna, Italy

4. Department of Neuroscience, Laboratory of Prion Biology, Scuola Internazionale Superiore di Studi Avanzati (SISSA), Via Bonomea 265, I-34136 Trieste, Italy

5. Biomedical Research Center, University Hospital Hradec Kralove, 500 00 Hradec Kralove, Czech Republic

6. Institute of Pharmaceutical Sciences, University of Freiburg, Albertstraße 25, 79104 Freiburg im Breisgau, Germany

7. Department of Pharmaceutical Science, University of Milan, Via Mangiagalli 25, 20133 Milan, Italy

Funder

Ministerstvo Zdravotnictv? Cesk? Republiky

Deutsche Forschungsgemeinschaft

Conselho Nacional de Desenvolvimento Cient?fico e Tecnol?gico

Universit? di Bologna

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Reference32 articles.

1. World Alzheimer report 2015 - the global impact of dementia: an analysis of prevalence, incidence, cost and trends. https://www.alz.co.uk/research/world-report-2015 (accessed March 2019).

2. Alzheimer's disease drug development pipeline: 2018

3. Facing Alzheimer’s disease in the developing countries.

4. Alzheimer’s disease drug-development pipeline: few candidates, frequent failures

5. Progress on dementia—leaving no one behind

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