Identification of RIPK3 Type II Inhibitors Using High-Throughput Mechanistic Studies in Hit Triage
Author:
Affiliation:
1. Bristol-Myers Squibb Research & Development, P.O. Box 4000, Princeton, New Jersey 08543, United States
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.9b00065
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1. Initiation and execution mechanisms of necroptosis: an overview
2. Regulated necrosis: disease relevance and therapeutic opportunities
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4. RIP1 Kinase Drives Macrophage-Mediated Adaptive Immune Tolerance in Pancreatic Cancer
5. Necroptotic cell death – An unexpected driver of pancreatic oncogenesis
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