Structure-Guided Design of Substituted Biphenyl Butanoic Acid Derivatives as Neprilysin Inhibitors-Reference-Cited by-同舟云学术

Structure-Guided Design of Substituted Biphenyl Butanoic Acid Derivatives as Neprilysin Inhibitors

Published:2020-01-27 Issue:2 Volume:11 Page:188-194
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Kawanami Toshio¹,Karki Rajeshri G.¹^ORCID,Cody Emma¹,Liu Qian¹,Liang Guiqing¹,Ksander Gary M.¹,Rigel Dean F.²,Schiering Nikolaus³,Gong Yongjin¹,Coppola Gary M.¹,Iwaki Yuki¹,Sun Robert¹,Neubert Alan¹,Fan Li¹,Ingles Sara³,D’Arcy Allan³,Villard Frederic³,Ramage Paul³,Jeng Arco Y.²,Leung-Chu Jennifer²,Liu Jing²,Beil Michael²,Fu Fumin²,Chen Wei²,Cumin Frederic³,Wiesmann Christian³,Mogi Muneto¹

Affiliation:

1. Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, United States

2. Novartis Pharmaceuticals Corporation, One Health Plaza, East Hanover, New Jersey 07936-1080, United States

3. Novartis Institutes for BioMedical Research, Novartis Campus, CH-4056 Basel, Switzerland

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.9b00578

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1. Therapeutic benefits of increasing natriuretic peptide levels