Structure–Activity Relationship for the Oxadiazole Class of Antibacterials

Author:

Boudreau Marc A.1,Ding Derong1,Meisel Jayda E.1,Janardhanan Jeshina1,Spink Edward1,Peng Zhihong1,Qian Yuanyuan1,Yamaguchi Takao1,Testero Sebastian A.1ORCID,O’Daniel Peter I.1,Leemans Erika1,Lastochkin Elena1,Song Wei1,Schroeder Valerie A.2,Wolter William R.2,Suckow Mark A.2,Mobashery Shahriar1ORCID,Chang Mayland1ORCID

Affiliation:

1. Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana 46556, United States

2. Freimann Life Sciences Center and Department of Biological Sciences, University of Notre Dame, Notre Dame, Indiana 46556, United States

Funder

National Institute of Allergy and Infectious Diseases

National Institute of General Medical Sciences

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Reference12 articles.

1. National Center for Health Statistics. National Vital Statistics Report. http://www.infoplease.com/ipa/A0005148.html.

2. Update on the antibiotic resistance crisis

3. Centers for Disease Control and Prevention. Antibiotic Resistance Threats in the United States, 2013; 2013.

4. Discovery of a New Class of Non-β-lactam Inhibitors of Penicillin-Binding Proteins with Gram-Positive Antibacterial Activity

5. Structure–Activity Relationship for the Oxadiazole Class of Antibiotics

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