Importance of Quantifying Drug-Target Engagement in Cells-Reference-Cited by-同舟云学术

登录注册会员服务联系我们

Importance of Quantifying Drug-Target Engagement in Cells

Published:2020-03-06 Issue:4 Volume:11 Page:403-406
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Stefaniak Jakub¹²³^ORCID,Huber Kilian V. M.¹²^ORCID

Affiliation:

1. Structural Genomics Consortium, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7DQ, U.K.

2. Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7FZ, U.K.

3. Chemistry Research Laboratory, University of Oxford, Oxford OX1 3TA, U.K.

Funder

Engineering and Physical Sciences Research Council

Medical Research Council

Wellcome

Innovative Medicines Initiative

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.9b00570

Reference19 articles.

1. Appraising iniparib, the PARP inhibitor that never was—what must we learn?

2. Activity-based protein profiling reveals off-target proteins of the FAAH inhibitor BIA 10-2474

3. A Call for Systematic Research on Solute Carriers

4. Lessons learned from the fate of AstraZeneca's drug pipeline: a five-dimensional framework

5. Target validation using chemical probes

Cited by 42 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. A Probe-Free Occupancy Assay to Assess a Targeted Covalent Inhibitor of Receptor Tyrosine-Protein Kinase erbB-2;ACS Pharmacology & Translational Science;2024-08-01

2. Development of a NanoBRET Assay Platform to Detect Intracellular Ligands for the Chemokine Receptors CCR6 and CXCR1;ChemMedChem;2024-07-24

3. Fluorophore-Labeled Pyrrolones Targeting the Intracellular Allosteric Binding Site of the Chemokine Receptor CCR1;ACS Pharmacology & Translational Science;2024-06-21

4. Improved drug target deconvolution with PISA‐DIA using an extended, overlapping temperature gradient;PROTEOMICS;2024-05-20

5. Synthesis of Monofluorinated 7-Hydroxycoumarin-3-Carboxamides as Cell-Permeable Fluorescent Molecular Probes;ACS Medicinal Chemistry Letters;2024-04-15

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号京ICP备18003416号-3