Targeting an Artificial Metal Nuclease to DNA by a Simple Chemical Modification and Its Drastic Effect on Catalysis
Author:
Affiliation:
1. Centro de Biologia Molecular Estrutural, Departamento de Bioquímica, Universidade Federal de Santa Catarina, 88040900 Florianópolis-SC, Brazil
2. Departamento de Química, Universidade Federal de Santa Catarina, 88040900 Florianópolis-SC, Brazil
Funder
Conselho Nacional de Desenvolvimento Cient?fico e Tecnol?gico
Financiadora de Estudos e Projetos
Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior
INCT Cat?lise
INCT Biologia Estrutural e Bioimagem
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.9b00289
Reference53 articles.
1. Metal complexes promoting catalytic cleavage of nucleic acids — biochemical tools and therapeutics
2. Catalytic Metallodrugs: Substrate-Selective Metal Catalysts as Therapeutics
3. Interactions of copper complexes with nucleic acids
4. CHEMICAL NUCLEASES: NEW REAGENTS IN MOLECULAR BIOLOGY
5. Mononuclear CuII−Phenolate Bioinspired Complex is Catalytically Promiscuous: Phosphodiester and Peptide Amide Bond Cleavage
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