A Novel Biphenyl-based Chemotype of Retinoid X Receptor Ligands Enables Subtype and Heterodimer Preferences-Reference-Cited by-同舟云学术

A Novel Biphenyl-based Chemotype of Retinoid X Receptor Ligands Enables Subtype and Heterodimer Preferences

Published:2019-08-16 Issue:9 Volume:10 Page:1346-1352
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Pollinger Julius¹,Schierle Simone¹,Gellrich Leonie¹,Ohrndorf Julia¹,Kaiser Astrid¹,Heitel Pascal¹^ORCID,Chaikuad Apirat¹^ORCID,Knapp Stefan¹^ORCID,Merk Daniel¹^ORCID

Affiliation:

1. Institute of Pharmaceutical Chemistry, Goethe University Frankfurt, Max-von-Laue-Str. 9, D-60438 Frankfurt, Germany

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.9b00306

Reference22 articles.

1. International Union of Pharmacology. LXIII. Retinoid X Receptors

2. Nuclear Receptors, RXR, and the Big Bang

3. Retinoid X receptor gamma signaling accelerates CNS remyelination

4. ApoE-Directed Therapeutics Rapidly Clear β-Amyloid and Reverse Deficits in AD Mouse Models

5. Bexarotene Induces Dyslipidemia by Increased Very Low-Density Lipoprotein Production and Cholesteryl Ester Transfer Protein-Mediated Reduction of High-Density Lipoprotein

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