Discovery of an Anion-Dependent Farnesyltransferase Inhibitor from a Phenotypic Screen
Author:
Affiliation:
1. MRL, Merck & Co., Inc., West Point, Pennsylvania 19486, United States
2. MRL, Merck & Co., Inc., Kenilworth, New Jersey, 07033, United States
3. MRL, Merck & Co., Inc., Boston, Massachusetts, 02115, United States
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.0c00551
Reference28 articles.
1. How were new medicines discovered?
2. Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening
3. The Resurrection of Phenotypic Drug Discovery
4. Phenotypic vs. Target-Based Drug Discovery for First-in-Class Medicines
5. Shocking HIV out of hiding
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