Lipid Tales: Optimizing Arylomycin Membrane Anchors-Reference-Cited by-同舟云学术

Lipid Tales: Optimizing Arylomycin Membrane Anchors

Published:2023-10-11 Issue:11 Volume:14 Page:1524-1530
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Koehler Michael F. T.¹^ORCID,Chen Yi-Chen²,Chen Yongsheng³,Chen Yuan²,Crawford James J.¹^ORCID,Durk Matthew R.²,Garland Keira¹,Hanan Emily J.¹^ORCID,Higuchi Robert I.⁴,Hu Huiyong¹,Ly Cuong Q.¹,Paraselli Prasuna G.⁴,Roberts Tucker C.⁴,Schwarz Jacob B.¹,Smith Peter A.⁵,Yu Zhiyong³,Heise Christopher E.⁶

Affiliation:

1. Department of Discovery Chemistry, Genentech, Inc., South San Francisco, California 94080, United States

2. Department of Drug Metabolism and Pharmacokinetics, Genentech, Inc., South San Francisco, California 94080, United States

3. Department of Chemistry, WuXi AppTec, Shanghai 200131, China

4. RQx Pharmaceuticals, La Jolla, California 92037, United States

5. Department of Infectious Disease, Genentech, Inc., South San Francisco, California 94080, United States

6. Department of Biochemical and Cellular Pharmacology, Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, United States

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.3c00327

Reference30 articles.

1. Global Antimicrobial Resistance and Use Surveillance System (GLASS) Report 2022; World Health Organization: Geneva, 2022.

2. The Science of Antibiotic Discovery

3. Novel Lipoglycopeptides as Inhibitors of Bacterial Signal Peptidase I

4. Arylomycins A and B, New Biaryl-bridged Lipopeptide Antibiotics Produced by Streptomyces sp. Tue 6075. II. Structure Elucidation.

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