Impact of Hydrogen Bonding on P-Glycoprotein Efflux Transport as Revealed by Evaluation of a De Novo Prediction Model-Reference-Cited by-同舟云学术

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Impact of Hydrogen Bonding on P-Glycoprotein Efflux Transport as Revealed by Evaluation of a De Novo Prediction Model

Published:2023-12-21 Issue:1 Volume:15 Page:54-59
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Gou Yulong¹^ORCID,Re Suyong²^ORCID,Mizuguchi Kenji¹²^ORCID,Nagao Chioko¹²^ORCID

Affiliation:

1. Institute for Protein Research, Osaka University, 3-2 Yamadaoka, Suita-shi, Osaka 565-0871, Japan

2. Artificial Intelligence Center for Health and Biomedical Research, National Institutes of Biomedical Innovation, Health and Nutrition, 17-3 Senrioka-Shinmachi, Settu-City, Osaka 566-0002 Japan

Funder

Japan Society for the Promotion of Science

Institute for Protein Research, Osaka University

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.3c00376

Reference23 articles.

1. ATP-DEPENDENT TRANSPORT SYSTEMS IN BACTERIA AND HUMANS: Relevance to Cystic Fibrosis and Multidrug Resistance

2. Expression of the multidrug resistance gene product (P-glycoprotein) in human normal and tumor tissues.

3. Functional expression and localization of P-glycoprotein at the blood brain barrier

4. Alzheimer's Disease: The Amyloid Cascade Hypothesis

5. THE BIOCHEMISTRY OF P-GLYCOPROTEIN-MEDIATED MULTIDRUG RESISTANCE

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