Targeted Combination Therapies: A New Frontier in the Treatment of TP53 and KRAS Mutation-Associated Cancers
Author:
Affiliation:
1. Usona Institute, Fitchburg, Wisconsin 53711-5300, United States
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.3c00534
Reference6 articles.
1. Recent advances in the development of inhibitors targeting KRAS-G12C and its related pathways
2. Restoration of p53 functions by suppression of mortalin–p53 sequestration: an emerging target in cancer therapy
3. KRAS G12C in advanced NSCLC: Prevalence, co-mutations, and testing
4. TP53-mutated acute myeloid leukemia and myelodysplastic syndrome: biology, treatment challenges, and upcoming approaches
5. Aligning germline and somatic mutations in prostate cancer. Are genetics changing practice?
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