Discovery and Characterization of Active CBP/EP300 Degraders Targeting the HAT Domain
Author:
Affiliation:
1. Department of Chemistry, University of Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland
2. Department of Biochemistry, University of Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland
Funder
Schweizerischer Nationalfonds zur F?rderung der Wissenschaftlichen Forschung
Krebsliga Schweiz
Publisher
American Chemical Society (ACS)
Link
https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.3c00490
Reference43 articles.
1. Protacs: Chimeric molecules that target proteins to the Skp1-Cullin-F box complex for ubiquitination and degradation
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2. Paralogue-Selective Degradation of the Lysine Acetyltransferase EP300;JACS Au;2024-07-29
3. Design, synthesis and biological evaluation of new RNF126-based p300/CBP degraders;Bioorganic Chemistry;2024-07
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