DegraderTCM: A Computationally Sparing Approach for Predicting Ternary Degradation Complexes
Author:
Affiliation:
1. University of Torino, Department of Molecular Biotechnology and Health Sciences, CASSMedChem, Piazza Nizza 44, 10126 Torino, Italy
Funder
Ministero dell?Istruzione, dell?Universit? e della Ricerca
Fondazione CRT
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.3c00362
Reference31 articles.
1. Advancing New Chemical Modalities into Clinical Studies
2. New Chemical Modalities and Strategic Thinking in Early Drug Discovery
3. The PROTAC gold rush
4. PROTAC targeted protein degraders: the past is prologue
5. Discovery of Highly Potent and Efficient PROTAC Degraders of Androgen Receptor (AR) by Employing Weak Binding Affinity VHL E3 Ligase Ligands
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