Synthesis and Biophysical Characterization of Fingolimod Derivatives as Cardiac Troponin Antagonists-Reference-Cited by-同舟云学术

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Synthesis and Biophysical Characterization of Fingolimod Derivatives as Cardiac Troponin Antagonists

Published:2024-02-07 Issue:3 Volume:15 Page:413-417
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Kondacs Laszlo¹,Parijat Priyanka²,Cobb Alexander J. A.¹^ORCID,Kampourakis Thomas²^ORCID

Affiliation:

1. Department of Chemistry, King’s College London, Britannia House, London SE1 1DB, United Kingdom

2. Randall Centre for Cell and Molecular Biophysics and British Heart Foundation Centre of Research Excellence, King’s College London, London SE1 1UL, United Kingdom

Funder

British Heart Foundation

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.3c00511

Reference19 articles.

1. Regulation of Contraction in Striated Muscle

2. Cardiac muscle thin filament structures reveal calcium regulatory mechanism

3. Targeting the sarcomere to correct muscle function

4. Structures reveal details of small molecule binding to cardiac troponin

5. 2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure

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