Repurposing of Raltitrexed as an Effective G9a/EHMT2 Inhibitor and Promising Anti-Alzheimer’s Agent-Reference-Cited by-同舟云学术

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Repurposing of Raltitrexed as an Effective G9a/EHMT2 Inhibitor and Promising Anti-Alzheimer’s Agent

Published:2023-10-12 Issue:11 Volume:14 Page:1531-1536
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Jana Abhisek¹,Bellver-Sanchis Aina²^ORCID,Griñán-Ferré Christian²³^ORCID,Banerjee Deb Ranjan¹^ORCID

Affiliation:

1. Department of Chemistry, National Institute of Technology Durgapur, M G Avenue, Durgapur-713209 , West Bengal, India

2. Pharmacology Section, Department of Pharmacology, Toxicology and Therapeutic Chemistry, Faculty of Pharmacy and Food Sciences, Institute of Neuroscience, Universitat de Barcelona (NeuroUB), Av. Joan XXIII 27−31, 08028 Barcelona, Spain

3. Centro de Investigación en Red, Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, 28029 Madrid, Spain

Funder

Science and Engineering Research Board

National Institute of Technology Durgapur

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.3c00344

Reference35 articles.

1. The Epigenomics of Cancer

2. An operational definition of epigenetics: Figure 1.

3. Chromatin Modifications and Their Function

4. The Mammalian Epigenome

5. Regulation of chromatin by histone modifications

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