Targeted Protein Degradation of Histone Deacetylases by Hydrophobically Tagged Inhibitors
Author:
Affiliation:
1. Department of Pharmaceutical and Cell Biological Chemistry, Pharmaceutical Institute, University of Bonn, An der Immenburg 4, 53121 Bonn, Germany
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.3c00468
Reference27 articles.
1. Histone Deacetylases (HDACs): Evolution, Specificity, Role in Transcriptional Complexes, and Pharmacological Actionability
2. Role of Class I and Class II histone deacetylases in carcinoma cells using siRNA
3. Role for Histone Deacetylase 1 in Human Tumor Cell Proliferation
4. HDAC family: What are the cancer relevant targets?
5. Synthesis of Peptoid-Based Class I-Selective Histone Deacetylase Inhibitors with Chemosensitizing Properties
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1. Development of peptoid-based heteroaryl-decorated histone deacetylase (HDAC) inhibitors with dual-stage antiplasmodial activity;European Journal of Medicinal Chemistry;2024-11
2. Hydrophobic tagging of small molecules: an overview of the literature and future outlook;Expert Opinion on Drug Discovery;2024-06-02
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