Discovery of Selective Tertiary Amide Inhibitors of Cyclin-Dependent Kinase 2 (CDK2)
Author:
Affiliation:
1. Genentech Inc., South San Francisco, California 94080, United States
2. Janssen R&D, 1400 McKean Rd, Spring House, Pennsylvania 19002, United States
3. Paraza Pharma Inc., Montreal, QC H4S 2E1, Canada
Funder
Genentech
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.3c00142
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1. To cycle or not to cycle: a critical decision in cancer
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4. Cellular mechanisms of tumour suppression by the retinoblastoma gene
5. Cyclin E1 and cyclin-dependent kinase 2 are critical for initiation, but not for progression of hepatocellular carcinoma
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