Discovery of a Tritiated Radioligand with High Affinity and Selectivity for the Histamine H<sub>3</sub> Receptor-Reference-Cited by-同舟云学术

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Discovery of a Tritiated Radioligand with High Affinity and Selectivity for the Histamine H₃ Receptor

Published:2023-10-17 Issue:11 Volume:14 Page:1589-1595
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Mönnich Denise¹,Nagl Martin¹,Forster Lisa¹,Rosier Niklas¹,Igel Patrick¹,Pockes Steffen¹²^ORCID

Affiliation:

1. Institute of Pharmacy, University of Regensburg, Universitätsstraße 31, 93053 Regensburg, Germany

2. Department of Medicinal Chemistry, Institute for Therapeutics Discovery and Development, University of Minnesota, Minneapolis, Minnesota 55414, United States

Funder

Elitenetzwerk Bayern

Fonds der Chemischen Industrie

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.3c00413

Reference40 articles.

1. Auto-inhibition of brain histamine release mediated by a novel class (H3) of histamine receptor

2. Sensitivity of histamine H3 receptor agonist-stimulated [35S]GTPγ[S]binding to pertussis toxin

3. Histamine modulates high-voltage-activated calcium channels in neurons dissociated from the rat tuberomammillary nucleus

4. H3-Receptors Control Histamine Release in Human Brain

5. Cloning and Functional Expression of the Human Histamine H3Receptor

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