Repurposing Azoles to Resolve Serotogenic Toxicity Associated with Linezolid to Combat Multidrug-Resistant Tuberculosis-Reference-Cited by-同舟云学术

Repurposing Azoles to Resolve Serotogenic Toxicity Associated with Linezolid to Combat Multidrug-Resistant Tuberculosis

Published:2023-11-01 Issue:12 Volume:14 Page:1754-1759
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Girase Rukaiyya T.¹,Ahmad Iqrar¹,Oh Jong Min²,Kim Hoon²,Mathew Bijo³^ORCID,Vagolu Siva K.⁴,Tønjum Tone⁴⁵^ORCID,Desai Nisheeth C.⁶,Sriram Dharmarajan⁷,Kumari Jyothi⁷,Patel Harun M.¹^ORCID

Affiliation:

1. Department of Pharmaceutical Chemistry, R. C. Patel Institute of Pharmaceutical Education and Research, Shirpur, Maharashtra India, 4254

2. Department of Pharmacy, and Research Institute of Life Pharmaceutical Sciences, Sunchon National University, Suncheon 57922, Republic of Korea

3. Department of Pharmaceutical Chemistry, Amrita School of Pharmacy, Amrita Vishwa Vidyapeetham, Kochi 690525, India

4. Department of Microbiology, University of Oslo, N-0316 Oslo, Norway

5. Department of Microbiology, Oslo University Hospital, N-0424 Oslo, Norway

6. Division of Medicinal Chemistry, Department of Chemistry (DST-FIST Sponsored), Maharaja Krishnakumarsinhji Bhavnagar University, Mahatma Gandhi Campus, Bhavnagar 364 002, India

7. Department of Pharmacy, Birla Institute of Technology and Science-Pilani, Hyderabad Campus, Jawahar Nagar, Shameerpet Mandal, R. R. District, Hyderabad 500078, India

Funder

University Grants Commission

Norges Forskningsr?d

H2020 Health

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.3c00406

Reference18 articles.

1. Discovery of a Conformationally Constrained Oxazolidinone with Improved Safety and Efficacy Profiles for the Treatment of Multidrug-Resistant Tuberculosis

2. Oxazolidinones as Anti-tubercular Agents: Discovery, Development and Future Perspectives

3. Oxazolidinone Structure–Activity Relationships Leading to Linezolid

4. Discovery of a Conformationally Constrained Oxazolidinone with Improved Safety and Efficacy Profiles for the Treatment of Multidrug-Resistant Tuberculosis

5. Antibacterial oxazolidinones: emerging structure–toxicity relationships