Targeting KRASG12D Mutations: Discovery of Small Molecule Inhibitors for the Potential Treatment of Intractable Cancers
Author:
Affiliation:
1. Usona Institute, Fitchburg, Wisconsin 53711-5300, United States
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.3c00277
Reference6 articles.
1. Targeting the ‘Undruggable’ Driver Protein, KRAS, in Epithelial Cancers: Current Perspective
2. KRAS G12D mutation in Brunner gland adenoma
3. KRAS G12D targeted therapies for pancreatic cancer: Has the fortress been conquered?
4. Expanding the Reach of Precision Oncology by Drugging All KRAS Mutants
5. Targeting KRAS in PDAC: A New Way to Cure It?
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1. In Silico Prediction of New Inhibitors for Kirsten Rat Sarcoma G12D Cancer Drug Target Using Machine Learning-Based Virtual Screening, Molecular Docking, and Molecular Dynamic Simulation Approaches;Pharmaceuticals;2024-04-25
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