Discovery of a GPR40 Superagonist: The Impact of Aryl Propionic Acid α-Fluorination-Reference-Cited by-同舟云学术

Discovery of a GPR40 Superagonist: The Impact of Aryl Propionic Acid α-Fluorination

Published:2018-12-03 Issue:1 Volume:10 Page:16-21
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Huang Hui,Meegalla Sanath K.,Lanter James C.,Winters Michael P.,Zhao Shuyuan,Littrell James,Qi Jenson,Rady Brian,Lee Paul S.,Liu Jianying,Martin Tonya,Lam Wing W.,Xu Fran,Lim Heng Keang,Wilde Thomas,Silva Jose,Otieno Monicah,Pocai Alessandro,Player Mark R.^ORCID

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.8b00444

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1. From the Triumvirate to the Ominous Octet: A New Paradigm for the Treatment of Type 2 Diabetes Mellitus

2. Safety of antidiabetes medications: An update

3. TAK-875 versus placebo or glimepiride in type 2 diabetes mellitus: a phase 2, randomised, double-blind, placebo-controlled trial

4. GPR40 agonists for the treatment of type 2 diabetes mellitus: The biological characteristics and the chemical space

5. Efficacy and safety of fasiglifam ( TAK ‐875), a G protein‐coupled receptor 40 agonist, in J apanese patients with type 2 diabetes inadequately controlled by diet and exercise: a randomized, double‐blind, placebo‐controlled, phase III trial

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