Enhanced Tumor Selectivity of 5-Fluorouracil Using a Reactive Oxygen Species-Activated Prodrug Approach-Reference-Cited by-同舟云学术

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Enhanced Tumor Selectivity of 5-Fluorouracil Using a Reactive Oxygen Species-Activated Prodrug Approach

Published:2018-12-03 Issue:1 Volume:10 Page:127-131
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Ai Yong¹,Obianom Obinna N.¹,Kuser Meredith¹,Li Yue²,Shu Yan¹³^ORCID,Xue Fengtian¹^ORCID

Affiliation:

1. Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, Maryland 21201, United States

2. Department of Chemistry and Biochemistry, University of Maryland College Park, College Park, Maryland 20740, United States

3. School and Hospital of Stomatology, Guangzhou Medical University, Guangzhou 510140, China

Funder

American Association for Cancer Research

Samuel Waxman Cancer Research Foundation

National Institute of General Medical Sciences

Leukemia Lymphoma Society

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.8b00539

Reference41 articles.

1. Fluorinated Pyrimidines, A New Class of Tumour-Inhibitory Compounds

2. 5-Fluorouracil: mechanisms of action and clinical strategies

3. Metabolism, Biochemical Actions, and Chemical Synthesis of Anticancer Nucleosides, Nucleotides, and Base Analogs

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