Synthesis of Artemisinin–Estrogen Hybrids Highly Active against HCMV, P. falciparum, and Cervical and Breast Cancer-Reference-Cited by-同舟云学术

Synthesis of Artemisinin–Estrogen Hybrids Highly Active against HCMV, P. falciparum, and Cervical and Breast Cancer

Published:2018-10-19 Issue:11 Volume:9 Page:1128-1133
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Fröhlich Tony¹,Kiss Anita²,Wölfling János²,Mernyák Erzsébet²,Kulmány Ágnes E.³,Minorics Renáta³,Zupkó István³,Leidenberger Maria⁴,Friedrich Oliver⁴,Kappes Barbara⁴,Hahn Friedrich⁵,Marschall Manfred⁵,Schneider Gyula²,Tsogoeva Svetlana B.¹^ORCID

Affiliation:

1. Organic Chemistry Chair I and Interdisciplinary Center for Molecular Materials (ICMM), Friedrich-Alexander University of Erlangen-Nürnberg, Nikolaus-Fiebiger-Straße 10, 91058 Erlangen, Germany

2. Department of Organic Chemistry, University of Szeged, Dóm tér 8, H-6720 Szeged, Hungary

3. Department of Pharmacodynamics and Biopharmacy, University of Szeged, Eötvös u. 6, H-6720 Szeged, Hungary

4. Institute of Medical Biotechnology, Friedrich-Alexander University of Erlangen-Nürnberg, Paul-Gordon-Straße 3, 91052 Erlangen, Germany

5. Institute for Clinical and Molecular Virology, Friedrich-Alexander University of Erlangen-Nürnberg, Schlossgarten 4, 91054 Erlangen, Germany

Funder

Gedeon Richter

Magyar Tudományos Akadémia

Országos Tudományos Kutatási Alapprogramok

Deutsche Forschungsgemeinschaft

Friedrich-Alexander-Universität Erlangen-Nürnberg

Interdisziplinäre Zentrum für Molekulare Materialien, Friedrich-Alexander-Universität Erlangen-Nürnberg

Graduate School of Molecular Science, Friedrich-Alexander-Universität Erlangen-Nürnberg

Nemzeti Kutatási, Fejlesztési és Innovációs Hivatal

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.8b00381

Reference58 articles.

1. Synthesis of monomeric and dimeric steroids containing [1,2,4]triazolo[1,5-a]pyrimidines

2. Design, synthesis, and biological evaluation of steroidal analogs as estrogenic/anti-estrogenic agents

3. Synthesis and Pharmacology of Anti-Inflammatory Steroidal Antedrugs

4. Synthesis of novel anti-inflammatory steroidal macrocycles using ring closing metathesis reaction

5. Arylmethylamino steroids as antiparasitic agents

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