Design, Synthesis, and Characterization of a Fluorescence Polarization Pan-BET Bromodomain Probe

Author:

Paulson Carolyn N.1,Guan Xianghong1,Ayoub Alex M.2,Chan Alice34,Karim Rezaul M.34,Pomerantz William C. K.2ORCID,Schönbrunn Ernst34ORCID,Georg Gunda I.1ORCID,Hawkinson Jon E.1ORCID

Affiliation:

1. Department of Medicinal Chemistry and Institute for Therapeutics Discovery & Development, College of Pharmacy, University of Minnesota, 717 Delaware Street SE, Minneapolis, Minnesota 55414, United States

2. Department of Chemistry, University of Minnesota, 207 Pleasant Street, SE, Minneapolis, Minnesota 55455, United States

3. H. Lee Moffitt Cancer Center & Research Institute, 12902 Magnolia Drive, Tampa, Florida 33612, United States

4. Department of Molecular Medicine, University of South Florida, Tampa, Florida 33612, United States

Funder

Division of Chemistry

National Institute of Child Health and Human Development

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

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