Synthesis of 5-Thio-α-GalCer Analogues with Fluorinated Acyl Chain on Lipid Residue and Their Biological Evaluation-Reference-Cited by-同舟云学术

Synthesis of 5-Thio-α-GalCer Analogues with Fluorinated Acyl Chain on Lipid Residue and Their Biological Evaluation

Published:2019-01-30 Issue:2 Volume:10 Page:221-225
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

He Peng¹,Zhao Chuanfang²,Lu Jiao³,Zhang Yang²,Fang Min³,Du Yuguo¹²⁴^ORCID

Affiliation:

1. State Key Laboratory of Environmental Chemistry and Eco-toxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Science, Beijing 100085, China

2. School of Chemical Sciences, University of Chinese Academy of Sciences, Beijing 100049, China

3. CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China

4. National Engineering Research Center for Carbohydrate Synthesis, Jiangxi Normal University, Nanchang 330022, Jiangxi, China

Funder

Ministry of Science and Technology of the People's Republic of China

National Natural Science Foundation of China

Chinese Academy of Sciences

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.8b00640

Reference29 articles.

1. The Biology of NKT Cells

2. The unique role of natural killer T cells in the response to microorganisms

3. Natural killer T cell-mediated antitumor immune responses and their clinical applications

4. Structure-Activity Relationship of .alpha.-Galactosylceramides against B16-Bearing Mice

5. 4,5-Cis Unsaturated α-GalCer Analogues Distinctly Lead to CD1d-Mediated Th1-Biased NKT Cell Responses

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4. Diversity-Oriented Synthesis of a Molecular Library of Immunomodulatory α-Galactosylceramides with Fluorous-Tag-Assisted Purification and Evaluation of Their Bioactivities in Regard to IL-2 Secretion;International Journal of Molecular Sciences;2022-11-02

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