First-of-its-kind STARD3 Inhibitor: In Silico Identification and Biological Evaluation as Anticancer Agent-Reference-Cited by-同舟云学术

First-of-its-kind STARD3 Inhibitor: In Silico Identification and Biological Evaluation as Anticancer Agent

Published:2019-02-20 Issue:4 Volume:10 Page:475-480
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Lapillo Margherita¹,Salis Barbara²³,Palazzolo Stefano²,Poli Giulio¹,Granchi Carlotta¹,Minutolo Filippo¹^ORCID,Rotondo Rossella²,Caligiuri Isabella²,Canzonieri Vincenzo²,Tuccinardi Tiziano¹^ORCID,Rizzolio Flavio²⁴

Affiliation:

1. Department of Pharmacy, University of Pisa, 56126 Pisa, Italy

2. Department of Translational Research, Pathology Unit, National Cancer Institute−CRO-IRCSS, 33081 Aviano, Italy

3. Doctoral School in Biomolecolar Medicine, University of Trieste, 34127 Trieste, Italy

4. Department of Molecular Sciences and Nanosystems, Ca’ Foscari University of Venezia, 30172 Mestre, Italy

Funder

Associazione Italiana per la Ricerca sul Cancro

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.8b00509

Reference29 articles.

1. Identification of Four Novel Human Genes Amplified and Overexpressed in Breast Carcinoma and Localized to the q11-q21.3 Region of Chromosome 17

2. Give lipids a START: the StAR-related lipid transfer (START) domain in mammals

3. Functional and Physiological Consequences of StAR Deficiency: Role in Lipoid Congenital Adrenal Hyperplasia

4. STARD 3 mediates endoplasmic reticulum‐to‐endosome cholesterol transport at membrane contact sites

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