Optimization of Preclinical Metabolism for Somatostatin Receptor Subtype 5-Selective Antagonists
Author:
Affiliation:
1. Merck & Co., Inc., Kenilworth, New Jersey 07033, United States
Funder
Merck
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.8b00306
Reference13 articles.
1. All Five Cloned Human Somatostatin Receptors (hSSTR1-5) Are Functionally Coupled to Adenylyl Cyclase
2. Advances in understanding neuronal somatostatin receptors
3. Expression and Distribution of Somatostatin Receptor Subtypes in the Pancreatic Islets of Mice and Rats
4. Somatostatin-28 regulates GLP-1 secretion via somatostatin receptor subtype 5 in rat intestinal cultures
5. Pancreatic Somatostatin Inhibits Insulin Secretion Via SSTR-5 in the Isolated Perfused Mouse Pancreas Model
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