Synthesis and Automated Labeling of [18F]Darapladib, a Lp-PLA2 Ligand, as Potential PET Imaging Tool of Atherosclerosis-Reference-Cited by-同舟云学术

Synthesis and Automated Labeling of [18F]Darapladib, a Lp-PLA2 Ligand, as Potential PET Imaging Tool of Atherosclerosis

Published:2019-04-04 Issue:5 Volume:10 Page:743-748
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Guibbal Florian¹^ORCID,Meneyrol Vincent²,Ait-Arsa Imade²,Diotel Nicolas¹,Patché Jessica¹,Veeren Bryan¹,Bénard Sébastien²,Gimié Fanny²,Yong-Sang Jennyfer¹,Khantalin Ilya³,Veerapen Reuben⁴,Jestin Emmanuelle¹²,Meilhac Olivier¹³

Affiliation:

1. Université de La Réunion, INSERM, UMR 1188 Diabète athérothrombose Thérapies Réunion Océan Indien (DéTROI), Saint-Denis de La Réunion, France

2. CYclotron Réunion Océan Indien CYROI, 2 rue Maxime Rivière, 97490 Sainte-Clotilde, France

3. CHU de La Réunion, Saint-Denis de La Réunion, France

4. Clinique de Sainte-Clotilde, 127, Route de Bois de Nèfles, Sainte-Clotilde, Réunion, France

Funder

European Regional Development Fund

Association Nationale de la Recherche et de la Technologie

Philancia Foundation

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.8b00643

Reference37 articles.

1. WHO Cardiovascular Diseases (CVDs). http://www.who.int/mediacentre/factsheets/fs317/en/.

2. Atherosclerosis — An Inflammatory Disease

3. Cardiovascular Imaging: A Glimpse into the Future

4. A 24-week study to evaluate the effect of rilapladib on cognition and cerebrospinal fluid biomarkers of Alzheimer's disease

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