Novel Aminoquinoline Derivatives Significantly Reduce Parasite Load in Leishmania infantum Infected Mice

Author:

Konstantinović Jelena1,Videnović Milica2,Orsini Stefania3,Bogojević Katarina1,D’Alessandro Sarah4,Scaccabarozzi Diletta5,Terzić Jovanović Nataša6,Gradoni Luigi3,Basilico Nicoletta1,Šolaja Bogdan A.17ORCID

Affiliation:

1. University of Belgrade, Faculty of Chemistry, Studentski trg 12-16, P.O. Box 51, 11158 Belgrade, Serbia

2. University of Belgrade, Faculty of Chemistry Innovative Centre, Studentski trg 12-16, 11158 Belgrade, Serbia

3. Unit of Vector-borne Diseases, Istituto Superiore di Sanità, Rome, Italy

4. Dipartimento di Scienze Biomediche, Chirurgiche e Odontoiatrichè, Università degli Studi di Milano, Milan, Italy

5. Dipartimento di Scienze Farmacologiche e Biomolecolari, Università degli Studi di Milano, Milan, Italy

6. University of Belgrade, Institute of Chemistry, Technology, and Metallurgy, Njegoševa 12, 11000 Belgrade, Serbia

7. Serbian Academy of Sciences and Arts, Knez Mihailova 35, 11158 Belgrade, Serbia

Funder

Ministero dell?Istruzione, dell?Universit? e della Ricerca

Ministarstvo Prosvete, Nauke i Tehnolo?kog Razvoja

Srpska akademija nauka i umetnosti

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Reference26 articles.

1. Leishmaniasis Fact Sheet N°375, February 2015. http://www.who.int/mediacentre/factsheets/fs375/en/ (accessed October 16, 2017).

2. Centers for Disease Control and Prevention, Parasites - Leishmaniasis, January 2013. http://www.cdc.gov/parasites/leishmaniasis/ (accessed October 16, 2017).

3. WHO Technical Report Series no. 949. Report of a Meeting of the WHO Expert Committee on the Control of Leishmaniases, Geneva, 22–26 March 2010. http://www.who.int/neglected_diseases/resources/who_trs_949/en/ (accessed October 16, 2017).

4. DNDi Portfolio December 2017. https://www.dndi.org/diseases-projects/portfolio/ (accessed March 22, 2018).

5. Antileishmanial drug discovery: comprehensive review of the last 10 years

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