Investigation around the Oxadiazole Core in the Discovery of a New Chemotype of Potent and Selective FXR Antagonists-Reference-Cited by-同舟云学术

Investigation around the Oxadiazole Core in the Discovery of a New Chemotype of Potent and Selective FXR Antagonists

Published:2019-01-10 Issue:4 Volume:10 Page:504-510
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Festa Carmen¹,Finamore Claudia¹,Marchianò Silvia²,Di Leva Francesco Saverio¹,Carino Adriana²,Monti Maria Chiara³^ORCID,del Gaudio Federica³,Ceccacci Sara³,Limongelli Vittorio¹⁴,Zampella Angela¹^ORCID,Fiorucci Stefano²,De Marino Simona¹^ORCID

Affiliation:

1. Department of Pharmacy, University of Naples “Federico II”, Via D. Montesano 49, Naples 80131, Italy

2. Department of Surgery and Biomedical Sciences, Nuova Facoltà di Medicina, Perugia 06132, Italy

3. Department of Pharmacy, University of Salerno, Via Giovanni Paolo II, 132, Fisciano, Salerno 84084, Italy

4. Faculty of Biomedical Sciences, Institute of Computational Science - Center for Computational Medicine in Cardiology, Università della Svizzera italiana (USI), Via G. Buffi 13, Lugano CH-6900, Switzerland

Funder

Schweizerischer Nationalfonds zur F?rderung der Wissenschaftlichen Forschung

Universit?? degli Studi di Napoli Federico II

Ministero dell'Istruzione, dell'Universit?? e della Ricerca

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.8b00534

Reference22 articles.

1. Identification of a nuclear receptor that is activated by farnesol metabolites