New Scaffold for Angiogenesis Inhibitors Discovered by Targeted Chemical Transformations of Wondonin Natural Products
Author:
Affiliation:
1. College of Pharmacy, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 08826, Korea
Funder
National Research Foundation of Korea
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.7b00281
Reference27 articles.
1. Natural Products As Sources of New Drugs over the 30 Years from 1981 to 2010
2. Wondonins A and B, new bis(dihydroxystyryl)imidazoles from a two-sponge association
3. Dihydroxystyrene Metabolites from an Association of the Sponges Poecillastra wondoensis and Jaspis sp.
4. Total Syntheses of Isowondonins Based on a Biosynthetic Pathway
5. Wondonin, a novel compound, inhibits hypoxia-induced angiogenesis through hypoxia-inducible factor 1 alpha
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