Pilot Plant Preparation of an αvβ3 Integrin Antagonist. Part 1. Process Research and Development of a (S)-β-Amino Acid Ester Intermediate: Synthesis via a Scalable, Diastereoselective Imino-Reformatsky Reaction-Reference-Cited by-同舟云学术

Pilot Plant Preparation of an αvβ3 Integrin Antagonist. Part 1. Process Research and Development of a (S)-β-Amino Acid Ester Intermediate: Synthesis via a Scalable, Diastereoselective Imino-Reformatsky Reaction

Published:2003-12-18 Issue:1 Volume:8 Page:51-61
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Clark Jerry D.¹,Weisenburger Gerald A.¹,Anderson D. Keith¹,Colson Pierre-Jean¹,Edney Albert D.¹,Gallagher Donald J.¹,Kleine H. Peter¹,Knable Carl M.¹,Lantz Melissa K.¹,Moore Christine M. V.¹,Murphy James B.¹,Rogers Thomas E.¹,Ruminski Peter G.¹,Shah Ajit S.¹,Storer Neil¹,Wise Bruce E.¹

Affiliation:

1. Global Research & Development, Pfizer Corporation, 2800 Plymouth Road, Ann Arbor, Michigan 48105, U.S.A., Global Research & Development, Pfizer Corporation, 4901 Searle Parkway, Skokie, Illinois 60077, U.S.A., Global Research & Development, Pfizer Corporation, 800 North Lindbergh Boulevard, St. Louis, Missouri 63167, U.S.A., Research and Development, Pfizer Corporation, 700 Chesterfield Parkway, Chesterfield, Missouri 63017, U.S.A., and Oxford Asymmetry International, 151 Milton Park, Abington, Oxon OX14...

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/op034094j

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