Anomalous Substituent Effects in the Bischler−Napieralski Reaction of 2-Aryl Aromatic Formamides

Author:

Ishikawa Tsutomu1,Shimooka Kazunari1,Narioka Tomoko1,Noguchi Shigeru1,Saito Tatsuru1,Ishikawa Akiko1,Yamazaki Emi1,Harayama Takashi1,Seki Hiroko1,Yamaguchi Kentaro1

Affiliation:

1. Faculty of Pharmaceutical Sciences and Chemical Analysis Center, Chiba University, 1-33 Yayoi, Inage, Chiba 263-8522 Japan

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Reference32 articles.

1. (a) Whaley, W. M.; Govindachari, T. R.Organic Reactions; Adams, R., Ed.; John-Wiley and Sons:  New York, 1951; Vol 6, pp 74−150.

2. Correlation of the von Braun, Ritter, Bischler-Napieralski, Beckmann and Schmidt reactions via nitrilium salt intermediates

3. (c) Fowler, F. W.Comprehensive Hetrocyclic Chemistry; Katrirzky, A. R.; Rees, C. W., Eds.; Pergamon Press:  Oxford, 1984; Vol 2, pp 410−416.

4. Studies on the chemical constituents of rutaceous plants. LX. Development of a versatile method for syntheses of the antitumor benzo(c)phenanthridine alkaloids. 9. Efficient syntheses and antitumor activities of nitidine and related nonphenolic benzo(c)phenanthridine alkaloids.

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