Design, Synthesis, and Biological Evaluation of Potent Dual Agonists of Nuclear and Membrane Bile Acid Receptors-Reference-Cited by-同舟云学术

Design, Synthesis, and Biological Evaluation of Potent Dual Agonists of Nuclear and Membrane Bile Acid Receptors

Published:2014-01-17 Issue:3 Volume:57 Page:937-954
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

D’Amore Claudio¹,Di Leva Francesco Saverio²,Sepe Valentina³,Renga Barbara¹,Del Gaudio Chiara³,D’Auria Maria Valeria³,Zampella Angela³,Fiorucci Stefano¹,Limongelli Vittorio³

Affiliation:

1. Dipartimento di Medicina Clinica e Sperimentale, Nuova Facoltà di Medicina, Università degli Studi di Perugia, Via Gambuli, 1-06132 Perugia, Italy

2. Drug Discovery and Development, Istituto Italiano di Tecnologia, Via Morego, 30, 16163 Genoa, Italy

3. Dipartimento di Farmacia, Università di Napoli “Federico II”, Via D. Montesano, 49, I-80131 Napoli, Italy

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm401873d

Reference74 articles.

1. Pleiotropic Roles of Bile Acids in Metabolism

2. Identification of a Nuclear Receptor for Bile Acids

3. Bile Acids: Natural Ligands for an Orphan Nuclear Receptor

4. Activation of the nuclear receptor FXR improves hyperglycemia and hyperlipidemia in diabetic mice

5. Glucocorticoid receptor mediates the gluconeogenic activity of the farnesoid X receptor in the fasting condition

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