Structure-Based Approach to the Development of Potent and Selective Inhibitors of Dihydrofolate Reductase from Cryptosporidium
Author:
Affiliation:
1. Department of Pharmaceutical Sciences and Department of Chemistry, University of Connecticut, Storrs, Connecticut 06269
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm8009124
Reference20 articles.
1. Cryptosporidiosis: An Emerging, Highly Infectious Threat
2. Epidemiology of Cryptosporidium: transmission, detection and identification
3. Targeting DHFR in parasitic protozoa
4. Treatment of intestinal parasitic infections: a review of nitazoxanide
5. Treatment of cryptosporidiosis in immunocompromised individuals: systematic review and meta-analysis
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