Synthesis and Evaluation of a Carbocyclic Analogue of the CC-1065 and Duocarmycin Alkylation Subunits: Role of the Vinylogous Amide and Implications on DNA Alkylation Catalysis
Author:
Affiliation:
1. Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/jo981698q
Reference37 articles.
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3. Duocarmycin SA, a new antitumor antibiotic from Streptomyces sp.
4. Pyrindamycins A and B, new antitumor antibiotics.
5. CC-1065 and the Duocarmycins: Understanding their Biological Function through Mechanistic Studies
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