Convergent Synthesis of the Quinolone Substructure of BILN 2061 via Carbonylative Sonogashira Coupling/Cyclization-Reference-Cited by-同舟云学术

Convergent Synthesis of the Quinolone Substructure of BILN 2061 via Carbonylative Sonogashira Coupling/Cyclization

Published:2006-05-20 Issue:13 Volume:71 Page:5031-5034
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Haddad Nizar¹,Tan Jonathan¹,Farina Vittorio¹

Affiliation:

1. Department of Chemical Development, Boehringer Ingelheim Pharmaceuticals Inc., 900 Ridgebury Rd., P.O. Box 368, Ridgefield, Connecticut 06877-0368 nhaddad@rdg.boehringer-ingelheim.com

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/jo060556q

Reference21 articles.

1. 136 Antiviral effect of BILN 2061, a novel HCV serine protease inhibitor, after oral treatment over 2 days in patients with chronic hepatitis C, non-genotype 1

2. An NS3 protease inhibitor with antiviral effects in humans infected with hepatitis C virus

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